While other forms of the pain reliever naproxen require you to take multiple doses throughout the day, NAPRELAN® delivers pain relief with just 1 convenient daily dose.1 You can expect your pain relief to begin within about 30 minutes of taking NAPRELAN®1.

Based on the cause of your pain, your doctor will prescribe the most appropriate dose of NAPRELAN® for the appropriate length of time. Always take your medicine exactly as your doctor has prescribed. Before you begin to take your medicine, be sure to read the Medication Guide that is included with your prescription.

NAPRELAN® may be used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, tendinitis, bursitis, and acute gout. It may also be used to relieve mild to moderate pain and the treatment of primary dysmenorrhea (menstrual cramps).
Important Safety Information
NAPRELAN®is a non-steroidal anti-inflammatory drug (NSAID). Like all NSAIDS, it can cause an increased risk of a heart attack or stroke that can lead to death. This risk may occur early in treatment and may increase by taking higher doses or with longer use.

NAPRELAN® should not be taken right before or after a heart surgery called a coronary artery bypass graft (CABG), or after a recent heart attack.

Bleeding, ulcers, and tears of the esophagus, stomach and intestines may occur without warning anytime during use and may cause death. These risks increase in patients taking certain medications, those who smoke or drink alcohol, and the elderly.

Tell your doctor if you have liver or kidney problems, high blood pressure, asthma, pregnant or plan to become pregnant or breastfeeding.

You should not take NAPRELAN® if you have had an asthma attack, hives or other allergic reaction with aspirin or any other NSAIDs.

NAPRELAN®can cause new or worse high blood pressure, heart failure, liver problems including liver failure, kidney problems including kidney failure, and low red blood cells (anemia). NAPRELAN® should not be taken after 29 weeks of pregnancy.

Life threatening allergic reactions, including serious skin reactions can occur with NAPRELAN®.
Other side effects of NSAIDs include stomach pain, constipation, diarrhea, gas, heartburn, nausea, vomiting, and dizziness.

Get emergency help right away if you have shortness of breath or trouble breathing, chest pain, weakness in one part or side of your body, slurred speech, swelling of the face or throat.

NAPRELAN®should be used exactly as prescribed at the lowest dose possible and for the shortest time needed.

These are not all the possible side effects. For more information, ask your doctor or pharmacist.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit or call 1-800-FDA-1088. You may also contact Almatica at 1-877-447-7979.
Click here for full Prescribing Information and Medication Guide
References: 1. NAPRELAN® [package insert]. 2009. 2. Gaston G. A double-blind, randomized, parallel-group study of the pharmacokinetics and onset of action of Naprelan in patients following oral surgery. Am J Orthop. 1996;25(suppl 9):37-41. 3. Lane NE, Schnitzer TJ. Osteoarthritis. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, PA: Elsevier; 2008:1993-1997.

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